by Dr. Christopher Lepisto

a 2-min read

In too many of my patients, antacids have been a quiet companion for years, even decades, in the management of their acid reflux. It may have started during a stressful season, after a bout of heartburn, or as a short-term solution that slowly became routine. Over time, taking an antacid can feel less like a choice and more like a necessity, something the body simply “needs” to function.

But what effect does that have on the body?

PPIs (proton-pump inhibitors) work by suppressing stomach acid production, which can certainly reduce discomfort in the short-term. What’s not typically discussed is that it is indicated for 12 weeks of use or less.

Long-term acid suppression has been associated with reduced absorption of nutrients like magnesium, calcium, iron, and B12, increased risk of infections, and changes in the gut microbiome. It can contribute to ongoing bloating, food sensitivities, and severe rebound reflux that reinforces continued use.

This doesn’t mean antacids are always the wrong choice. But when use extends over many years without addressing underlying causes, the original reason for starting is often forgotten, while new symptoms and worsening side effects develop.

In naturopathic medicine, supporting recovery from long-term antacids (or any medication, for that matter) is a gradual process, not a quick fix. It involves a careful digestive support strategy over time—rarely abrupt discontinuation—including targeted nutrition and gentle ways to restore stomach acidity naturally.

Just as important is addressing inflammation and healing the gut lining—work that realistically takes at least several months.

If you’ve been taking antacids for years and still don’t feel well digestively, it may be a sign that your body needs a different kind of support. Sometimes the most productive next step is an informed conversation—one that looks at where you started, how your body has adapted, and what a thoughtful, natural recovery path could look like for you.